Our Management

Jim Reid, Chairman & CEO


Winner of the Ernst & Young Entrepreneur of the Year for Science and Technology for both Scotland and at the UK National finals in 2005, Jim has had a successful international career in the pharmaceutical and biotechnology industries. A Biochemist and Pharmacologist by training, Jim developed his early career in blue-chip organisations including Organon, Roche and Alcan in many parts of the world progressing from the research bench to business management before returning to Scotland in 1999. Since then he has utilised this experience to contribute widely to the exciting life sciences industry there. Jim was instrumental in the formation and development of more than 10 companies in the sector and has successfully exited from 3 of these companies, including the highly acclaimed sale of Haptogen to Wyeth, one of the world’s top pharmaceutical companies. Jim is now expanding his work with early stage Life Science companies hopefully picking the “winners” of the future in this key sector of the Scottish economy. He is a Global Scot, an Ambassador of the Saltire Fellowship and was the recipient of the 2010 Outstanding Contribution to Scottish Life Science award.

Vincent O'Brien, CSO & COO


Vincent is a co-founder of Sistemic and was formerly a Senior Fellow at Imperial College London where he continued research into acquired drug resistance, epigenetic therapies and biomarker discovery began at the Centre for Oncology and Applied Pharmacology at the University of Glasgow. His research management career began at the Beatson Institute in Glasgow where following a period of post-doctoral work in the US he spent 3 years as an Independent Investigator. Vincent has BSc and PhD degrees in Biochemistry and an MSc in IT Systems with over 3 years commercial IT experience. He has published and presented extensively and won both SMART Feasibility and R&D grant awards from the Scottish Government.

David Mallinson, Principal Scientist


David joined Sistemic in May 2011 as a Principal Research Scientist. David is primarily responsible for organizing and co-ordinating the wet lab work, bioinformatics analysis and final output for client projects. Prior to joining Sistemic David worked for over 20 years as a molecular and cell biologist in both academic Research Institutes and the Pharmaceutical Industry. Working across diverse biological areas, as well as, the drug discovery process, has provided David with an in-depth biological knowledge and expertise of the drug discovery process across a wide range of disease/therapeutic areas including neuroscience, immunology and cardiovascular. A key area of expertise for David, with direct relevance in the cell therapy space, is the identification and application of translational efficacy/potency biomarkers, both pre-clinically and clinically.

Donald Dunbar, Senior Bioinformatician


Donald leads the informatics team at Sistemic. A biologist by training, Donald moved into the field whilst working as a Drug Discovery scientist at Organon Laboratories. After seven years at Organon, Donald left to take up a position, leading bioinformatics in the Queen’s Medical Research Institute at the University of Edinburgh. While at Edinburgh, Donald was central in developing bioinformatics approaches to medical research questions in cardiovascular, inflammation and reproductive biology, and he still retains close links with the academic community there. Returning to academia allowed Donald to continue to build an excellent publication record with papers in high impact journals. After nine successful years leading the bioinformatics team, Donald left academia to develop the bioinformatics approaches of Sistemic.